SNHG7, SNHG8, and SNHG25, like MALAT1 and NEAT1, are positive regulators of inflammation and negative regulators of immunological response, implying a function in moderating the inflammatory response within the COVID-19 patients’ classical monocytes, DC, naive B/T, activated CD4 + T, and class switched memory B cells (28,46,47). The gene discussed is CD4; the disease is COVID-19.