CD8A and neoplasm: At D7, we observed a significant increase in total CD45+ leukocyte, CD3+ T lymphocyte and CD8+ T cytotoxic cells infiltration in the combined exercise-immuno-chemotherapy group tumors compared to immune-chemotherapy alone, suggesting that that one week of exercise before immuno-chemotherapy administration is sufficient to increase total leukocyte and T lymphocyte tumor infiltration included the CD8+ cytotoxic T cells.