In addition, these cells also share other receptors with innate NK cells such as FcγRIIIa (CD16) which is required to recognize opsonized tumor cells, DNAX accessory molecule (DNAM-1, CD226) and natural cytotoxicity receptors (NCRs) NKp46, NKp44 and NKp30 which promote anti-tumor cytotoxicity (5, 6). The gene discussed is CD226; the disease is neoplasm.