In addition, a significant positive correlation was noted between CXCR5+TIM-3-PD-1+ CD8+ T cell counts and proportions in paranasal sinus mucosa and nasal polyps from the same patient (percentage: r=0.748, p=0.033; number: r=0.970, p=0.0001; Figures 6A–D). This evidence concerns the gene PDCD1 and Nasal polyposis.