BCHE and Alzheimer disease: Anthraquinone (AQ) metabolites can be found in various plant species, with a higher concentration in families such as Rubiaceae, Polygonaceae, and Rhamnaceae. AD patients may benefit from AQ-based compounds because they inhibit cholinesterase, reduce protein aggregate formation, and suppress ROS production, which can mitigate the loss of cholinergic function [14].