PRL and Breast hypertrophy: Increased estrogen levels during pregnancy contribute to gestational gigantomastia, potentially treated with tamoxifen, although its efficacy is uncertain.5, 6Bromocriptine is used to reduce prolactin levels and can stabilize the condition until the end of pregnancy, without increasing the risk of miscarriage or birth defects.4The effectiveness of nonsteroidal anti-inflammatory drugs or corticosteroids for autoimmune-related cases remains inconclusive.5, 7