Although the posterior probability of shared causal variants within ± 500kb windows of the HMGCR gene region (PP.H4 = 7.576% in discovery dataset; PP.H4 = 0.022% in replication dataset) was low, the probability of colocalization conditional on the presence of a causal variant for hyperthyroidism [PP.H4/(PP.H3 + PP.H4)] exceeded 75% (82.980% in discovery dataset; 75.124% in replication dataset), providing suggestive evidence for colocalization. Here, HMGCR is linked to hyperthyroidism.