GALT activity in the late prenatal stage in various organs of a sheep model (Coelho et al., 2017) showed that galactosemia acute target organs–liver, small intestine and kidney–had the highest late prenatal activity, whereas the chronic target organs–brain and ovary–did not exhibit a noticeable pre- or postnatal different activity, in line with the notion that some organs/cells have a greater susceptibility to impaired galactose metabolism. The gene discussed is GALT; the disease is classic galactosemia.