In addition, C5AR1, CSF1R, CSF2RB, CYBB, HCK, ITGB2, LILRB2, MNDA, MPEG1, PLEK, and SRGN exhibited notable upregulation in GC cells (AGS, SGC7901 and MKN28) compared with those in GES-1 cells, with remarkable downregulation of STAB1 expression (Figure 5). The gene discussed is PLEK; the disease is gastric cancer.