People with intellectual disabilities have several risk factors for developing problems with constipation.5 Factors associated with constipation in people with intellectual disabilities from previous studies include profound intellectual disability, cerebral palsy, lack of mobility, Down syndrome, certain medications (including anti-epileptic medication, benzodiazepines, histamine H2-receptor antagonists and proton pump inhibitors) and non-ambulatory status.9 This evidence concerns the gene HRH2 and Intellectual disability.