MEX3C and neoplasm: To further analyze the relationship between tumor progression and MEX3C, its transcription was silenced in A549 and H1299 cells and verified with qRT-PCR and western blotting analysis, si-MEX3C-3 showed the highest interference efficiency in both A549 and H1299 cell lines and was picked up for further experiments and named si-MEX3C (Fig. 2B).