On the other hand, TAMs can also activate the epithelial mesenchymal transition (EMT) in tumors through chemokines and cytokines, such as TGF-β, IL-10, IL-6, matrix metalloproteinases (MMPs), and vascular endothelial growth factor (VEGF), to promote tumor invasion and migration [17–20]. This evidence concerns the gene VEGFA and neoplasm.