SOD1 and chronic obstructive pulmonary disease: Ismail et al. [59] also revealed that 1 g/d of SP administration for 2 months significantly reduced serum content of lipid peroxidation products and improved the antioxidant-related activity of enzymes, such as SOD and glutathione-s-transferase (GST) in patients with chronic obstructive pulmonary disease (COPD).