Advanced prostate cancer incidence for Asian men with a raised PSA result was 4.5% (95% CI: 3.8%, 5.3%) compared with 7.5% for White men (95% CI: 7.3%, 7.8%) and 7.0% for Black men (95% CI: 6.1%, 7.8%), using age-based thresholds. Here, KLK3 is linked to Familial prostate cancer.