CD4 and neoplasm: Moreover, both CD8 T cells in the tumor-draining lymph node (TDLN) (Supplementary Fig. 2B) and CD4 T cells in the tumor (Fig. 2C) and TDLN (Supplementary Fig. 2C), showed an increase in IFN-γ expression in CD244fl/flLysMcre mice compared to CD244fl/fl mice.