These findings could be verified in a linear regression model that indicated an independent association of preoperative BChE activity with age (B = -12.383 (95% CI: -21.937 to -2.829), p = 0.011), history of stroke (B = -516.173 (95% CI: -893.927 to -138.420), p = 0.008) and a positive history of alcohol abuse (B = -451.466 (95% CI: -868.380 to -34.551), p = 0.034). The gene discussed is BCHE; the disease is alcohol abuse.