LDLR and congenital bilateral aplasia of vas deferens from CFTR mutation: Beyond mice, Watanabe heritable hyperlipidemic (WHHL) rabbits (Rajamannan et al. 2005) and pigs with mutated LDLR and/or apolipoprotein genes (Grunwald et al. 1999; Prescott et al. 1991) are also employed in CAVD research.