Bioinformatic analysis of TCGA data indicated that NAMPT-high ovarian cancer patients had several elevated genesets involved with inflammatory response (Fig. 4A–C and Supplementary Fig. 3A,, B), while PAK4-high ovarian patients had increased expression of genesets related to DNA replication/repair, mTORC1-signaling, Wnt-β-Catenin signaling, and PI3K-AKT signaling (Fig. 4D–F and Supplementary Fig. 3C,, D). The gene discussed is NAMPT; the disease is ovarian cancer.