In accordance with these observations, the expression of key HCC glucose transporters (slc2a1, slc2a2 and slc2a3), as well as of key glycolytic enzymes (hk2, gpi, pfk, aldoa, pkm2) was strongly up regulated in ChREBP overexpressing tumors (Fig. 6l and Supplementary Fig. 9a). The gene discussed is ALDOA; the disease is hepatocellular carcinoma.