ALB and neoplasm: developed albumin-dye nanoparticles (HSA-Croc) by pH-sensitivecroconaine (Croc) dye self-assembled with HSA.427 While under acidic conditions, Croc dye has strong absorptionat 790 nm and HSA-Croc nanoparticles exhibit accurate tumor-specificphotoacoustic imaging and PTT.