ALB and neoplasm: Lin et al. developed a multifunctionalBAC prodrug that combines the chemotherapeutic drug camptothecin (CPT)and the fluorescent photothermal agent BODIPY through hypoxia-responsiveazobenzene linkers.447 This prodrug wasthen encapsulated in human serum albumin to generate nanoparticles(HSA@BAC) to enhance solubility and tumor accumulation.