We also conducted MR analysis with the exclusion of SNPs associated with T2D (rs13389219, rs17036160, rs2943652, rs56094641 and rs58542926), fasting insulin (rs4841132) and hypertension (rs7653249) in the MASLD IVs and two T2D-related SNPs (rs1802295 and rs8100204) in the liver fibrosis and cirrhosis IVs. The gene discussed is INS; the disease is Cirrhosis.