Moreover, exogenous administration of miR-30e, miR-190, miR-7 suppresses the generation of IL-1β and IL-18 in PD by inhibiting NLRP3, ASC, caspase-1 protein levels (Li et al. 2018; Zhou et al. 2016b; Sun et al. 2019) (Fig 3). The gene discussed is CASP1; the disease is Parkinson disease.