CD28 and hepatocellular carcinoma: High expression of CD28 (P=6.83e-06), CD27 (P=0.000), CD244 (P=0.002), PDCD1LG2 (P=0.003), CD86 (P=0.005), and CD48 (P=0.007) was shown in a Kaplan-Meier plot to be substantially linked with a better prognosis for HCC, while high expression of TNFSF4 (P=2.93e-07) and NRP1 (P=0.007) illustrated opposite survival outcome (Figure 6D).