Sample cohort 2 included 51 NOH, 11 MOH, and 10 SOH participants, who showed no significant differences in gender, age, education, hypertension, stroke, ACE‐III, MMSE, MOCA, memory, attention, language fluency, language, visuospatial function, Aβ42, Aβ40, p‐tau, GFAF, NFL, Aβ42/Aβ40, and α‐synuclein (p > 0.05), but statistically significant differences in hypertension, supine SBP, supine DBP, ΔSBP, and ΔDBP among the three groups (p < 0.05) (Table 2). The gene discussed is MAPT; the disease is stroke disorder.