DEPs, including GNAQ (G protein subunit α Q), CA3 (carbonic anhydrase 3), ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5), and SPTB (spectrin β) were identified in total participants between recurrence and nonrecurrence patients with ischemic stroke (Table S1). Here, CA3 is linked to ischemic stroke.