The latter includes genes such as EPH receptor B4 (Ephb4, 2.0-fold downregulated), a signaling pathway reported to allow podocytes to survive transient capillary collapse during glomerular disease (37), actin filament-associated protein 1-like 2 (Afap1l2, 1.6-fold downregulated), ephrin A5 (Efna5, 2.3-fold downregulated), and GATA binding protein 3 (Gata3, 2.7-fold downregulated). The gene discussed is AFAP1L2; the disease is glomerular disorder.