While identifying and correcting preoperative risk factors has been a hot topic of concern, current mainstream research (2, 7, 18) has primarily focused on identifying independent risk factors that are difficult to modify or intervene upon, such as advanced age, male gender, dementia, diabetes, ASA classification, and inflammatory indicators such as neutrophil count, lymphocyte count, and C-reactive protein. The gene discussed is CRP; the disease is diabetes mellitus.