GYS1 and neoplasm: Additionally, numerous studies have shown that GYS1 participates in tumor growth and progression through different mechanisms such as via the nuclear factor kappa‐B (NF‐κB) pathway, the AMP‐activated protein kinase (AMPK) pathway, and the hypoxic inducible factor‐1 alpha (HIF‐1α) pathway.26, 27, 28