CD274 and neoplasm: A special interest in the selection of CPI therapy is given to the PD-L1 score, which indicates the expression of PD-L1 on tumor cells by specifying TPS (percentage of PD-L1-positive tumor cells from all vital tumor cells), IC (percentage of area of PD-L1-positive immune cells from area of vital tumor cells), and CPS (combination of TPS and IC, percentage of PD-L1-positive cells, including lymphocytes and macrophages from all vital tumor cells) quantified in the expression of PD-L1 on the tumor cells and the immune cells infiltrating them.