NOS2 and colitis: Treatment with crocetin after the initiation of colitis by 2, 4, 6-trinitrobenzene sulfonic acid (TNBS) resulted in a reduction in the levels of malondialdehyde (MDA), the expression of TH1 and TH2 cytokines, and inducible NO synthase due to the down-regulation of nuclear factor kappa B (NF-κB).