TFEB and Alzheimer disease: Lin Wenjia's [144] research found that the acupuncture points GV24 and bilateral GB13 can alleviate memory impairment related to Alzheimer's disease by promoting the autophagic clearance of Aβ and NLRP3 inflammasomes mediated by TFEB/TFE3.Although the relationship between mitochondrial autophagy and the pathogenesis of AD is still under investigation, acupuncture's regulation of mitochondrial autophagy-mediated clearance of dysfunctional mitochondria has shown potential for intervening in the treatment of AD.