CIRBP and cancer: To test above-mentioned hypothesis, we first evaluated the effects of Cirbp silencing by RNAi (Fig. S6) on the sensitivity of NPC cells and cancer stem-like cells to hyperthermia in vitro by CCK-8 assay (Fig. 4E), colony formation assay (Fig. 4F and Fig. S7A) and tumorsphere formation assay (Fig. 4G and Fig. S7B).