More interestingly, we clearly observed there was no statistically significant difference in tumor size (Fig. 8B,E), tumor volume (Fig. 8C, F) and tumor weight (Fig. 8D, G) of tumor xenografts formed by CNE2 or SUNE1 cells between LV-Cirbp + ICG group and LV-Cirbp group, suggesting that exogenous expression of Cirbp completely rescued hyperthermia-induced significant inhibition in tumor xenograft growth. Here, CIRBP is linked to neoplasm.