The enforced expression of Cirbp alone had little impact on the expression of stem cell-related markers (i.e., Nanog and Bmi-1) or slightly upregulated the expression of Sox2, Oct4 and ABCG2 in whole xenograft tumor lysates from CNE2 cells (Fig. 9C), as compared to those of control group (i.e., LV-con group). This evidence concerns the gene SOX2 and neoplasm.