CIRBP and nasopharyngeal carcinoma: As shown in Fig. 4A, the results from qRT-PCR assay revealed that miR-142-3p and miR-143 were significantly upregulated, and Cirbp was remarkably downregulated in hyperthermia-treated NPC cells (i.e., CNE2, SUNE1 and HONE1-EBV).