The multiple immunofluorescences of orthotopic tumor showed a higher expression of STAMBPL1, TRAF2 and β-catenin in the negative control group compared with the shSTAMBPL1 group were detected, and the higher expression of STAMBPL1, TRAF2 and β-catenin in the STAMBPL1 overexpressing group was also detected, as opposed to the negative control group (Fig. 11I, J). The gene discussed is STAMBPL1; the disease is neoplasm.