The expression of STAMBPL1 in HCC tissues with TP53-Mutant or TP53-NonMutant all showed a higher expression than normal liver tissues, and the STAMBPL1 is highly expressed in TP53 mutant HCC specimen compared with TP53-nonmutant type (Fig. 1J). The gene discussed is STAMBPL1; the disease is hepatocellular carcinoma.