PDGFB and colorectal carcinoma: Based on the correlation analysis of CRC tissue samples in TCGA database, it was found that RUNX1 was significantly correlated with PDGFB (P = 3.4e-30, R = 0.55), PDGFRA (P = 1.9e-28, R = 0.53) and PDGFRB (P = 4.6e-44, R = 0.64) (Fig. 4D).