TBC1D5 levels can also affect the OS and DFS in different subgroups of ccRCC’s TNM stage, tumor stage, and histologic grade (Additional file 3: Fig. S3). Further, TBC1D5 expression level in normal adjacent tissue of different malignant degree is comparable (Additional file 4: Fig. S4). This evidence concerns the gene TBC1D5 and nonpapillary renal cell carcinoma.