CERS2 and carcinoma: Based on the results of the TCGA and GTEx data analyses (Fig. 1B) and previous studies reporting that the mRNA levels of LASS2 during cell signalling processes do not always correspond to protein levels or enzyme activity [20, 21], we selected the carcinomas with the most significant differences in LASS2 expression (Fig. 1B) to explore the correlation between the LASS2 protein level and prognosis.