CERS2 and neoplasm: Western blot analysis confirmed that LASS2 overexpression upregulated the expression of the EMT marker protein E-Cadherin and downregulated the expression of N-Cadherin, vimentin, Snail, and Slug, whereas the addition of ferroptosis agonists or inhibitors significantly rescued the effect of LASS2 (Fig. 7A–D) in the tumour cell lines.