This score was significantly higher than that of t(8;21) CBF AML (p = 5.49 × 10−4), which is noteworthy because inv(16) AML typically exhibits a myelomonocytic (M4) differentiation, while t(8;21) CBF leukemia is usually more myeloid (M2) (Fig. 1D)30. The gene discussed is CEBPZ; the disease is leukemia.