Among them, ACSL3, CYP7A1, CYP27A1, FABP6, ME1, MMP1, NR1H3 and PPARG were highly expressed in HCC tissues, while FABP5, HMGCS2 and SLC27A5 were highly expressed in adjacent tissues (Fig. 1B). The gene discussed is CYP7A1; the disease is hepatocellular carcinoma.