AOPEP and lung adenocarcinoma: MiR-214 acts in cell growth, Pro, and Apo. Studies have indicated that the level of miR-214 is down-regulated in lung adenocarcinoma, and interference with miR-214 causes reduced Pro ability of lung adenocarcinoma cells and promotes cell Apo, suggesting that miR-214 can promote the Pro of lung adenocarcinoma cells while also possessing an anti-apoptotic effect31.