Being a target for HMGCR inhibitors, the MVA pathway may exert interesting therapeutic potential for treatment and prevention of BC, since statins can affect a wide range of molecular processes such as inflammation, cell migration, proliferation, apoptosis, angiogenesis and stemness by means of cholesterol-mediated and non-mediated pathways (Zaky et al 2023). The gene discussed is HMGCR; the disease is breast cancer.