Interestingly, among these proteins, there were the Heparin cofactor 2, Immunoglobulin heavy constant mu, the platelet factor 4, Filamin-A and Actin, cytoplasmic 1, Thymosin beta-4 which locus maps within the deleted region of chromosome 22 and found to be strongly associated with psychosis. The gene discussed is IGHM; the disease is psychotic disorder.