CREB5 and neoplasm: To identify the GBM anatomical region where CREB5 is preferentially expressed, we compared its expression patterns in the leading edge (LE), infiltrating tumor (IT), cellular tumor (CT), perinecrotic zone (PNZ), pseudopalisading cells around necrosis (PAN), hyperplastic blood vessels in cellular tumors (HBV), and microvascular proliferation (MVP) using the Ivy Glioblastoma Atlas Project dataset.