The involvement of Tfh cells in response to anti-PD-1 mAb in lymph nodes represents an intriguing parallel to some recent observations made at the tumor site (Cohen et al., 2022; Gu-Trantien et al., 2013; Magen et al., 2022, Preprint; Niogret et al., 2021; Sánchez-Alonso et al., 2020). Here, RPL17 is linked to neoplasm.