To further unveil the function of CPSF6 in virus-triggered innate immune responses, we measured the levels of phosphorylated IRF3 and TBK1 and observed that CPSF6 deficiency markedly facilitated TBK1 and IRF3 phosphorylation after VSV-eGFP infection (S6E Fig). This evidence concerns the gene CPSF6 and infection.