CPSF6 and infection: The data indicated that all the members of the CFIm complex exhibited decreased expression upon infection with VSV (vesicular stomatitis virus) or HSV-1 (herpes simplex virus 1) (Fig 1A and 1B) or stimulation with the nucleic acid analogue Poly (I:C) LMW (low molecular weight) or HSV60 (synthetic herpes simplex virus 1 DNA analogue) in BMDMs (mouse bone marrow-derived macrophages) (Fig 1C and 1D).