Furthermore, LDLR-mediated LDL cholesterol, also demonstrated a suggestive association with OA of the hip or knee (OR = 0.882, 95%CI: 0.788 to 0.988, p = 0.03, q = 0.07) and hip osteoarthritis (OR = 0.867, 95%CI: 0.769 to 0.978, p = 0.02, q = 0.07). The gene discussed is LDLR; the disease is osteoarthritis, hip.