Before embarking on these studies, we defined a number of desired characteristics of the virus to resemble known properties of MeV as observed in humans and NHPs, based on previously published data (6, –, 8, 27, 29, –, 32): (i) CDV should use CD150 and nectin-4, and (ii) the infection should be self-limiting, i.e., non-lethal. Here, NECTIN4 is linked to infection.