Using univariate Cox analysis, we demonstrated the relationship between WSCD2 protein expression (hazard ratio [HR] = 0.351, p < 0.001), age (HR = 2.305, p < 0.001), gender (HR = 1.698, p = 0.008), IDH1-R132H status (HR = 0.653, p = 0.027), CD68+ macrophages (HR = 1.833, p = 0.003), and tumor grade (HR = 1.890, p < 0.001) and the lifespan of the patients with glioma. This evidence concerns the gene CD68 and glioma.