BRCA2 and neoplasm: In total, 13 patients (13%) carried a P/LP variant in a known autosomal dominant tumor predisposition gene: APC (n = 1), BRCA2 (n = 2), CHEK2 (n = 4), DICER1 (n = 4), HOXB13 (n = 1), and MITF (n = 1).