Numerous palmitoylated proteins play a crucial role in IFN-γ, Nucleotide oligomerization domain (NOD)-like receptors 1 and 2 (NOD1/2), Stimulator of interferon genes (STING), and JAK-STAT signaling pathways, which are closely associated with anti-tumor immunity (3, 89). Here, IFNG is linked to neoplasm.