On multivariable logistic regression analysis, low baseline red blood cell (RBC) count, low baseline hematocrit, low baseline hemoglobin, and BRCA1/2 mutation were significantly associated with the development of grade 3+ anemia, while high baseline RBC, high baseline hematocrit, high baseline hemoglobin level and BRCA1/2 mutation were significantly associated with grade 1+ anemia [41]. Here, BRCA1 is linked to anemia (phenotype).